Joint work led by Prof. Kim HW and Hyun JK reported the effective role of nanoceria optimally dosed to a contused spinal cord of rat in restoring the function. This work was published in Advanced Science, 2017, 8, 1700034, with the title ‘Functional Recovery of Contused Spinal Cord in Rat with the Injection of Optimal-Dosed Cerium Oxide Nanoparticles'.
A review article in Nano Today entitled ‘Extra- and intra-cellular fate of nanocarriers under dynamic interactions with biology’, provides insight into how the nanoparticles can journey along the biological barriers in extra and intracellular space with specific mechanisms, and how to design new nanoparticles for delivery purpose.
NRF grants successfully funded for:
Dr.Singh RK : Self-fluorescent and multi-imaging silica-based composite nanoparticles for cancer theranostics (2017-2020)
Dr.KimTH : Anti-inflammatory nanoparticles with drug and gene delivery capacity (2016-2019)
Dr.S Prakash Parthiban: Engineered fibrillar microenvironment to probe cell polarity under three dimensional conditions (2016-2019)
Microspheres developed to release silicate ions demonstrated excellent angiogenic effects in vitro and in vivo, suggesting the potential implication of silicate ions in stimulating angiogenesis. Moreover, the silicate ions synergize with VEGF, evidenced by the co-delivery approach. This research was published in Biomaterials, by Dashnyam K et al.
Speaker : Dr. Hyoung Woo Choi, ITREN
Location : Room 103 Pharmacy Building, Dankook University
Abstract: Inorganic biomaterial is one of the leading used materials for tissue regeneration, biosensing substrate, and drug delivery carrier and surface modification technique is a key factor to improve the inherent property. Among the various inorganic biomaterials, hydroxyapatite nano-crystal is very frequently used for bone tissue engineering and drug delivery system.
The use of hydroxyapatite nano-crystal not only plays a significant role in maintaining the mechanical properties of the natural bone but also offers a favorable environment for osteocoduction, protein adhesion, and osteoblast proliferation. In addition, the feature that an acidic environment induces the dissolution of hydroxyapatite nano-crystal into nontoxic ions has attracted researchers to the develop various pH-responsive drugs and gene delivery system.
Here I will introduce a novel approach to the fabrication of porous scaffolds with surface-immobilized nano-hydroxyapatite is developed for effective bone tissue engineering and light-responsive gatekeeper for smart nitric oxide delivery using hydroxyapatite and mesoporous silica nano-particle. The hydroxyapatite coating on mesoporous silica surface is expected to act as a shielding layer for the nitric oxide donors but is degraded by acids generated from chemical reagent, which induce exposure of the nitric oxide donors to the physical environment.
Basic information about NK cell development and activation
Recent trends in cancer immunotherapy: animal experiments and clinical data
Possible solution to problems in present NK cell approaches to cancer
Therapy: NK cell engineering and culture/maintaining systems
Personal Note: Especially, I have been interested in 3D culture system for immune cells including NK cells. This could be a main topic for the meeting.
ITREN PhD Course Application Guide
3. Start of date
석/박사 대학원생 지원 가이드라인
We offer a position of 'Research Professorship' and 'Post-doc fellowship' for those who are passionate and eager to work at ITREN.
Let's make together something difference and amazing things happen with you.
1) Research Professors
2) Post-doctoral Fellows
2. Field of Research and Specialization
1) Cell reprogramming
2) Biomaterial synthesis (synthetic hydrogel, etc.)
3) Protein engineering
4) Neural cells, stem cells
5) Animal studies (neuro-muscular-skeletal system)
6) Any research area related with biomaterials, cell engineering
• Feel free to contact us with any inquiry
• Salary (30,000$~50,000$/year) depending on his/her ability and experiences
• Project incentives (~1,000$~3,000S, depending on published papers and government research grants)
• International collaborative researches with Columbia, UPenn, UCL, Sydney Univ.
4) 전문연구요원 (자체 TO 보유, 병무청 허가 기관)
2) 생체재료합성 (하이드로젤, 고분자 등)
3) 신경세포, 줄기세포 연구
4) 동물실험 (신경, 근육 재생 중심)
5) 기타 세포공학, 생체물리 등
• CV (논문 목록), 자기소개서, 연구계획을 이메일로 송부
• 연봉 3천~5천 (세전), 경험과 능력에 따라 계약
• 인센티브 (논문 및 연구비 수주에 따라, 약 1백~5백만)
• 과제내용에 따라 해외파견 근무 (Columbia, Uppen, UCL, Syndy 등)