Research ability of
Mechanobiology Dental Medicine
Control of ECM and Physical factor
- Regulation of physical/chemical ECM ligands
- Control of intrinsic/extrinsic force in a cell
- Relationship between regeneration and nanstructure
- Delivery system using functional meterials
- Differntiation research depending on mechanobiological stimulation
3D coluture and bio-mimic structure
- ECM mimic nano-fibril study
- Dynamic 3D hydrogel decelopmnt
- Scaffold of bio-degradable ECM development
- Patient-specific brain organoid developmnet
- Realtime assessment of micro-force in a cell
Mechanobiology signal pathway
- YAP-dependent inflamatory rehulation
- Fibrosis and cancer research via YAP signaling
- Piezo expression in electric stimulation
- Nuclear mechanics in cell reprograming
Mechanism study on tissue regeneration
- Vasular regeneration
- Bone regeneration
- Cartilage regeneration
- Central/peripheral nerve regeneration
Oral and dental regeneration study
- Periodontal tissue regeneration
- Pulp-dentin complex regeneration
- Dental stem cell signal pathway
- TMJ inflammation regulation
- Oral-maxillofacial regeneration
Establishment of preclinical study model
- Tooth injury model
- inflamatory pulp tissue model
- Ectopic pulp regeneration model
- Periodontal ligament injury model
- Other disease animal models(Myocardial infarction, strke, diabetes, acute/chronic kidney disease, nerve injury, hepatitis, etc.)