Feature Articles @ITREN in 2018~2023 (최근 5년간 출간된 하이라이트 논문 40편)
Advanced Science (2023) Cyclic stretch promotes cellular reprogramming process through cytoskeletal-nuclear mechao-coupling...
Park SM, Lee JH*, Ahn GS,..., Shim H*, Kim HW*
Trends in Biotechnology (2023) Advanced materials technologies to unravel mechanobiological phenomena
Kim HS, Taghizadeh A, Taghizadeh M, Kim HW*
Advanced Functional Materials (2023) Coordinated Biophysical Stimulation of MSCs via Electromagnetized Au-Nanofiber Matrix Regulates Cytoskeletal-to-Nuclear Mechanoresponses and Lineage Specification
Singh RK*, Kurian AG, Sagar V, ..., Lee JH*, Kim HW *
Bioactive Materials (2023) Double hits with bioactive nanozyme based on cobalt-doped nanoglass for acute and diabetic wound therapies through anti-inflammatory and pro-angiogenic functions
Mandakhbayar N, Ji Y, ..., Lee JH*, Kim HW*
Materials Today Bio (2023) Multifunctional dendrimer@nanoceria engineered GelMA hydrogel accelerates bone regeneration through orchestrated cellular responses
Kurian AG, Mandakhbayar N, Singh RK*, Lee JH*, Jin G, Kim HW*
Chemical Engineering Journal (2023) Electroconductive and mechano-competent PUCL@CNT nanohybrid scaffolds guiding neuronal specification
Li YM, Patel KD, Han YG, ... Lee JH*, Kim HW*
Biomaterials (2023) Mechano-modulation of T cells for cancer immunotherapy
Hyun J*, Kim SJ, Cho SD, Kim HW*
Progress in Materials Science (2023) Materials-based nanotherapeutics for injured and diseased bone
Lee CS, Sing RK, ... Kim HS*, Lee M*, Kim HW*
Advanced Healthcare Materials (2023) Delivery of Induced Neural Stem Cells Through Mechano-tuned Silk-collagen Hydrogels...
Davaa G, Hong JY, Lee JH,... Hyun JK*, Kim HW*
Biomaterials (2022) Nanoceria-GO-intercalated multicellular spheroids revascularize and salvage critical ischemic limbs through anti-apoptotic...
Bayaraa O, Dashnyam K, Singh RK,...Lee JH, Kim HW*
Matter (2022) Matrix-enabled mechanobiological modulation of osteoimmunology
Jung-Hwan Lee, Jae Hee Park, Jun Hee Lee, Hae-Hyoung Lee, Jonathan C Knowles, Hae-Won Kim
Biomaterials (2022) Chemically-induced osteogenic cells for bone tissue engineering and disease modeling
Yoon JY, Mandakhbayar N, Hyun J, ..., Lee JH*, Leong KW, Kim HW*
Bioactive Materials (2022) Dendritic cell-mimicking scaffolds for ex vivo T cell expansion
Kim HS, Ho TC, ..., Kim HW, Leong KW*
Advanced Healthcare Materials (2022) Mimicking Bone Extracellular Matrix: From BMP-2-Derived Sequences...
Oliver-Cervelló L, Martin-Gómez H, ...,Kim HW, Ginebra MP, Lee JH, Mas-Moruno C*
Biomaterials (2022) Diabetic bone regeneration with nanoceria-tailored scaffolds by recapitulating cellular microenvironment...
Singh RK, Yoon DS, Mandakhbayar N,... Lee JH*, Kim HW*
Bioactive Materials (2022) Materials and extracellular matrix rigidity highlighted in...
Park JH, Jo S, Lee JH, Lee HH, Knowles JC, Kim HW*
Bioengineering & Translational Medicine (2022) Hyperelastic, shape‐memorable, and ultra‐cell‐adhesive...
Hong SM, Yoon JY, Cha JR, ..., Lee JH*, Kim HW*
Cell Death & Differentiation (2022) TLR4 downregulation by the RNA-binding protein PUM1...
Yoon DS, ..., Lee JH, Kim HW*, Lee JW*
Trends in Molecular Medicine (2022) Leveraging cellular mechano-responsiveness for cancer therapy
Hyun J, Kim HW*
- 2023 1st Semester Beomjeong Academic Thesis Award Research Encouragement Scholarship
- ITREN students received the 2023 Spring Semester Beomjeong Academic Thesis Award Research Encouragement Scholarship on May 03, 2023.
Jae-Hee Park (Combined Ms&PhD course, 5th semester): Best Excellence Award (최우수상)
Oyunchimeg Bayaraa (PhD course, 9th semester): Excellence Award (우수상)
- 2023 April, Award from Korean Society for Dental Materials
- ITREN students successfully participated in the conference organised by the Korean Society of Dental Materials and received the awards on April 29, 2023.
Jae-Hee Park (Combined Ms&PhD course, 5th semester): Oral Presentation Award
Title: ''Novel Strategy for dental pulp regeneration with conditioned media derived from human gingival fibroblasts''
Buuvee Bayarkhangai (PhD course, 5th semester): Best Poster Presentation award
Title: "Enhancing antimicrobial activity via UV Treatment of Silane-treated zinc-oxide Nanoflakes"
Xiangting Fu (PhD course, 4th semester): Excellence award
Title: ''Nanoporcelain fringe on gelatin methacryloyl employed ROS scavenging properties applied in bone therapy''
- Prof. Jung-Hwan Lee elected as a new member of Young Korean Academy of Science and Technology (Y-KAST)
- Professor Jung-Hwan Lee of Dankook University has been officially elected as a new member of the Young Korean Academy of Science and Technology (Y-KAST). The Korean Academy of Science and Technology selects young researchers who have shown outstanding achievements in the field of science and technology every year as Y-KAST members. Y-KAST is a prestigious academic organization for future leaders in the development of science and technology in Korea. Professor Jung-Hwan Lee is an emerging researcher in field of biomaterials and he has identified various mechanisms related to the development and application of implantable biomaterials for tissue regeneration. Over the past two years, he has published more than 10 papers in the top journals such as Progress in Materials Science (IF=48.1), Matter (IF=19.9), Biomaterials (IF=15.3), Bioactive Materials (IF=16.8) and Chemical Engineering Journal (IF=16.7). Once again, congratulations on Prof. Jung-Hwan Lee for becoming a proud member of Y-KAST.
- (2022.09. People) Dr. Rajendra Kumar Singh, Dr. Dong Suk Yoon and Dr. Nandin Mandakbayar at ITREN developed a ROS-responsive nanoceria decorated scaffold based on 3D printing for hastening regeneration of critical sized bone defects in diabetic animals
- Dr. Rajendra Kumar Singh, Dr. Dong Suk Yoon and Dr. Nandin Mandakbayar at ITREN developed ROS-responsive nanoceria decorated scaffold based on 3D printing for hastening regeneration of critical sized bone defects in diabetic animals. The study recently got published in journal Biomaterials (IF:15.304) under the title “Diabetic bone regeneration with nanoceria-tailored scaffolds by recapitulating cellular microenvironment: Activating integrin/TGF-β co-signaling of MSCs while relieving oxidative stress. (Read the article online: https://doi.org/10.1016/j.biomaterials.2022.121732).
Regenerating defective bones in diabetic patients is of boundless clinical importance. The elevated blood glucose levels and oxidative stress in defected bones hinders the neo bone regeneration process and hence developing a therapeutic biomaterial that modulates oxidative stress while supporting osteogenesis is of great interest. This motivated Dr. Rajendra Kumar Singh, Dr. Dong Suk Yoon and Dr. Nandin Mandakbayar to challenge the problem by fabricating nanoceria decorated 3D-printed PCL scaffolds as a biomaterial for bone therapeutics. The entire study was conducted under the guidance of Prof. Hae-Won Kim and Prof. Jung-Hwan Lee here at ITREN. The excellent ROS-responsiveness and the nano-topological cues provided by scaffolds directed MSCS to express higher levels of focal adhesion proteins, curvature-sensing membrane proteins and significantly higher levels of osteogenic differentiation through integrin-mediated TGF-β co-signaling activation pathway. Such regulatory effects in MSC were further proven invivo by implantation in critical-sized bone defects of diabetic animals. Together all, the studies revealed that the currently exploited nCe-scaffolds can be a promising drug- and cell-free therapeutic means to treat defective tissues like bone in diabetic conditions.
- (2022.09. People) Dr. Suk-Min Hong, Dr. Ji-Young Yoon, and Dr. Jae-Ryung Cha at ITREN developed a novel polycaprolactone-based polyurethane (PCL-PU) copolymers with shape-memory, hyperelasticity, and ultra-cell-adhesion properties intended for various tissue regeneration applications
- Dr. Suk-Min Hong, Dr. Ji-Young Yoon, and Dr. Jae-Ryung Cha at ITREN developed polycaprolactone-based polyurethane (PCL-PU) copolymers with excellent shape-memory, hyper-elasticity, and ultra-cell-adhesion properties intended for various tissue regeneration applications. The study recently got published in journal Bioengineering &Translational medicine (IF: 10.684) under the title “Hyperelastic, shape-memorable, and ultra-cell-adhesive degradable polycaprolactone-polyurethane copolymer for tissue regeneration” (Read the article online: https://doi.org/10.1002/btm2.10332).
The PCL-PU biomaterial developed have shown prominent mechanical properties (~ 50 MPa tensile strength and ~ 1150% elongation with hyper-elasticity under cyclic load). The shape-memory features were also proved in film, thread, and 3D scaffold forms. With extensive invitro experiments, authors revealed the ultra-cell-adhesive properties and tissue regenerative potential by performing differentiation towards myogenic and osteogenic lineages. Furthermore, tissue compatibility, immune responses, and regenerative potential was investigated in-vivo. This study suggests the multifunctional roles of PCL-PU as a therapeutic biomaterial exclusively for minimally invasive surgeries that demands minor skin openings to target large defects along with promoting excellent tissue regeneration.