Major

• Molecular Cell Biology, Hepatology

Degree

• Bachelor Degree: From Pusan National University (2006.3-2010.8)
• Masters Degree: From Pusan National Univ. (2011.3-2013.2)
• Ph.D: From Pusan National Univ. (2013.3-2016.2)

Career

• (2016.3-2016.8) - Lecturer in Cell Biology, Pusan National University, Republic of Korea
• (2016-2017) - Postdoc., BK21 Plus Research Group Longevity and Marine Biotechnology, Pusan National University, Republic of Korea
• (2017-2020) - Postdoc., Division of Gastroenterology, Department of Medicine, Duke University, USA
• (2020~current) - Assistant Professor, Institute of Tissue Regeneration Engineering (ITREN), Dankook University, Republic of Korea

Selected Papers

• [22] Epithelial splicing regulatory protein 2-mediated alternative splicing reprograms hepatocytes in severe alcoholic hepatitis. J Clin Invest. (2020)
• [21] Single-Cell RNA Sequencing Identifies Yes-Associated Protein 1-Dependent Hepatic Mesothelial Progenitors in Fibrolamellar Carcinoma. Am J Pathol. (2020)
• [20] Increased Glutaminolysis Marks Active Scarring in Nonalcoholic Steatohepatitis Progression. Cell Mol Gastroenterol Hepatol. (2019)
• [19] Dysregulated Activation of Fetal Liver Program in Acute Liver Failure. Gut. (2019)
• [18] RNA Binding Proteins Control Transdifferentiation of Hepatic Stellate Cells into Myofibroblasts. Cell Physiol Biochem. (2018)
• [17] MicroRNA-378 is involved in hedgehog-driven epithelial-to-mesenchymal transition in hepatocytes of regenerating liver. Cell Death Dis. (2018)
• [16] Hedgehog-YAP Signaling Pathway Regulates Glutaminolysis to Control Activation of Hepatic Stellate Cells. Gastroenterology. (2018)
• [15] Tumor necrosis factor-inducible gene 6 protein ameliorates chronic liver damage by promoting autophagy formation in mice. Exp Mol Med. (2017)
• [14] Thymosin beta-4 regulates activation of hepatic stellate cells via hedgehog signaling. Sci Rep. (2017)
• [13] Hedgehog Signaling is Associated with Liver Response to Fractionated Irradiation in Mice. Cell Physiol Biochem. (2016)
• [12] MicroRNAs in liver fibrosis: Focusing on the interaction with hedgehog signaling. World J Gastroenterol. (2016)
• [11] Kombucha tea prevents obese mice from developing hepatic steatosis and liver damage. Food Sci Biotechnol. (2016)
• [10] MicroRNA expression profiling in CCl4-inducedliverfibrosisofMus musculus. Int J Mol Sci. (2016)
• [9] MicroRNA-378 limits activation of hepatic stellate cells and liver fibrosis by suppressing Gli3 expression. Nat Commun. (2016)
• [8] MicroRNA125b-mediated Hedgehog signaling influences liver regeneration by chorionic plate-derived mesenchymal stem cells. Sci Rep. (2015)
• [7] Tumor necrosis factor-inducible gene 6 promotes liver regeneration in mice with acute liver injury. Stem Cell Res Ther. (2015)
• [6] Hepatic stellate cells express thymosin Beta 4 in chronically damaged liver. PLoS One. (2015)
• [5] Potential role of Hedgehog signaling and microRNA-29 in liver fibrosis of IKKβ-deficient mouse. J Mol Histol. (2014)
• [4] Hedgehog signaling influences gender-specific response of liver to radiation in mice. Hepatol Int. (2013)
• [3] Potential role of Hedgehog pathway in liver response to radiation. PLoS One. (2013)
• [2] Hedgehog signaling regulates the repair response in mouse liver damaged by irradiation. Radiat Res. (2013)
• [1] Potential roles of hedgehog and estrogen in regulating the progression of fatty liver disease. J Life Sci. (Korean) (2011)