In article number 2303395, Jung-Hwan Lee, Hosup Shim, Hae-Won Kim, co-workers revealed that cyclic stretching of cells during reprogramming process significantly enhanced the efficiency of iPSC production through mechanotransduction molecules along the cytoskeletal-nuclear axis by epigenetic changes. This mechanical cell-engineering aids in mass-production of iPSCs and regenerative medicine.

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단국치대 연구진, 세포리포로그래밍 주제로 커버 논문 ‘화제’ (dailydental.co.kr)