About

Therapeutically relevant scaffolds and biomatrices hold great promise in tissue regeneration. This is possible by the internal or external modulation. Intrinsically, tuning chemical and physical properties, tethering active moieties and matching stiffness are the proper strategies. On the other hand, therapeutic drugs and growth factors can be combined with the matrices to deliver to target sites in a controllable, sustainable, and sequential manner, to control the complex events in repair and regeneration processes, such as anti-inflammation, angiogenesis, cell mitosis, migration, and differentiation. Therapeutic cues thus need to be considered relevant to target tissues and range control from molecular and ionic levels to morphological and geometrical parameters.